Lilly plans big Alzheimer’s disease study after prior failures

Eli Lilly and Co plans this year to begin a new late-stage trial of solanezumab, its experimental treatment for Alzheimer’s disease that failed in earlier testing to significantly slow progression of the memory-robbing disease, the U.S. drugmaker said on Friday.

A pair of unsuccessful earlier Phase III studies last summer had involved patients with mild to moderate symptoms. But combined data from them showed the drug slowed cognitive decline by 34 percent in patients who started out with only mild symptoms, but without slowing declines in their ability to perform everyday tasks.

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